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More model informationThis is DNMT1 (DNA methyltransferase 1). it’s a protein involved in the process of DNA methylation, which is the addition of a methyl group to cytosine residues in DNA. DNMT1 is responsible for maintaining the pattern of DNA methylation during DNA replication by transferring methyl groups to newly synthesized DNA strands, this process being crucial for genetic stability, gene expression and development.
Here we look at some of its key domains and interactions.
Zhang, Z. M., Liu, S., Lin, K., Luo, Y., Perry, J. J., Wang, Y., & Song, J. (2015). Crystal structure of human DNA methyltransferase 1. Journal of Molecular Biology, 427(15), 2520-2531. https://doi.org/10.1016/j.jmb.2015.06.001
Mar 26th 2023
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