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More model informationThis model explores the findings of the Han et al. (2017) paper that investigates the features of the PETase enzyme catalytic mechanism.
PET Hydrolase, or PETase, is one of the two enzymes found in the organism Ideonella sakaiensis that could potentially open up a pathway for breaking down PET plastic. After binding to PET, the enzyme breaks of down a monomer of the chain into mono-2-hydroxyethyl terephthalate, or MHET. This product can then be further broken down by its neighbouring enzyme, MHETase. One by one these enzymes degrade the polymer fibres of PET by each monomer to produce a product that can be more easily broken down.
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