PDB ID: 3W14
Insulin receptor ectodomain construct comprising domains L1,CR,L2, FNIII-1 and alphact peptide in complex with bovine insulin and FAB 83-14
Deposited: 2012-11-06 Released: 2013-01-09
Deposition author(s): Lawrence, M.C., Smith, B.J. Organism: Bos taurus | Mus musculus | Homo sapiens Expression System: Mus musculus, Cricetulus griseus, Mus musculus
Method: X-RAY DIFFRACTION
Resolution: 4.4 Å
R-Value Free: 0.262
R-Value Work: 0.245
Primary Citation
How insulin engages its primary binding site on the insulin receptor
Menting, J.G., Whittaker, J., Margetts, M.B., Whittaker, L.J., Kong, G.K.-W., Smith, B.J., Watson, C.J., Zakova, L., Kletvikova, E., Jiracek, J., Chan, S.J., Steiner, D.F., Dodson, G.G., Brzozowski, A.M., Weiss, M.A., Ward, C.W., Lawrence, M.C.
Nature 493: 241-245 (2013)
Comments