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More model informationThe first protein we investigated that was directly relating to cancer, HRAS1 is an oncogene that has GTPase activity. The Ras oncogene family is involved in signalling pathways and can cause oncogenesis when mutated. HRAS plays an important role in cell division, differentiation, and apoptosis. Here shown is an X-ray crystallography structure of amino acids 1-166 of HRAS1.
U. Krengel (1991) STRUKTUR UND GUANOSINTRIPHOSPHAT-HYDROLYSEMECHANISMUS DES C-TERMINAL VERKUERZTEN MENSCHLICHEN KREBSPROTEINS P21-H-RAS doi: 10.2210/pdb121p/pdb
Nov 2nd 2021
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