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More model informationCDX2 is a relatively small protein that binds to a short sequence of DNA. It acts as a transcription factor, playing a role in intestinal development.
DNA sequences that differ slightly tend to exhibit very different binding capabilities to one specific transcription factor, especially that of relatively small proteins. Yet CDX2 exhibits the ability to bind to two differing sequences…
The optimal sequences where CDX2 binds are GCAATAAA and CTCGTAAA. This model shows CDX2 binding to the GCAATAAA sequence.
CDX2 contains residues that form some interesting interactions between the residues, DNA and water molecules, which affect its ability to interact with its DNA sequences.
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